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Secondary sex determination

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NCBI Bookshelf. Primary sex determination is the determination of the gonads. In mammals, primary sex determination is strictly chromosomal and is not usually influenced by the environment. In most cases, the female is XX and the male is XY. Every individual must have at least one X chromosome.
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Sexual differentiation in humans

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Snapshot Summary: Sex Determination - Developmental Biology - NCBI Bookshelf

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Sex determination is a fundamentally important and highly diversified biological process, yet the mechanisms behind the origin of this diversity are mostly unknown.
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The evolution of sex determination associated with a chromosomal inversion

Metrics details. Primary sex determination in placental mammals is a very well studied developmental process. Here, we aim to investigate the currently established scenario and to assess its adequacy to fully recover the observed phenotypes, in the wild type and perturbed situations. Computational modelling allows clarifying network dynamics, elucidating crucial temporal constrains as well as interplay between core regulatory modules.
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NCBI Bookshelf. In mammals, primary sex determination the determination of gonadal sex is a function of the sex chromosomes. XX individuals are females, XY individuals are males. The Y chromosome plays a key role in male sex determination.
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